All models are wrong, but are they useful? Assessing reliability across multiple sites to build trust in urban drainage modelling

Simulation models are widely used in urban drainage engineering and research, Shirt but they are known to include errors and uncertainties that are not yet fully realised.Within the herein developed framework, we investigate model adequacy across multiple sites by comparing model results with measurements for three model objectives, namely surcharg

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Extracellular proteolysis of tandemly duplicated pheromone propeptides affords additional complexity to bacterial quorum sensing.

Bacterial interactions are vital for adapting to changing environments, with quorum sensing (QS) systems playing a central role in coordinating behaviors through small signaling molecules.The RRNPPA family is Selector Knob the prevalent QS systems in Bacillota and mediating communication through secreted oligopeptides, which are processed into acti

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Dual-sided electrosurgery handpiece for simultaneous tissue cutting and coagulation: first report on a conceptual design validated by an animal experiment

Hatem A Tawfik,1 Yousef A Fouad,2 Rashad Hafez3 1Department of Ophthalmology, Selector Knob Oculoplastics Service, Ain Shams University, 2Faculty of Medicine, Ain Shams University, 3Eye Subspecialty Centre, Cairo, Egypt Objective: To introduce and evaluate the safety of a novel dual-sided electrosurgery handpiece design for simultaneous tissue cutt

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Hunting for Sulfur-containing Molecules in Space: A Spectroscopic Characterization of Cyclopropenethione Based on High-level Ab Initio Calculations

Cyclopropenethione falls Coolers into the class of complex organic molecules but has not yet been observed in the interstellar medium or any circumstellar disks.However, its existence is very likely, and thus this study provides high-level ab initio predictions, which may serve as reference data for future observations or experimental work.Rovibrat

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